Search results for " Caspofungin"

showing 3 items of 3 documents

Caspofungin for the treatment of candidaemia in patients with haematological malignancies

2010

AbstractThis study was prospectively conducted in 11 haematology divisions over a 2-year period to evaluate the efficacy of caspofungin in 24 neutropenic patients with haematological malignancies (HM) and candidaemia. These patients had received chemotherapy for HM and were neutropenic (PNN < 0.5 × 109/L) for a median of 12 days (2–41) before candidaemia. The patients received caspofungin for a median duration of 12 days (range 6–26), obtaining a favourable overall response of 58%. At 30 days, 11 patients had died (46%); candidaemia was responsible for mortality in six patients (25%). These results suggest that treatment of candidaemia with caspofungin in neutropenic HM was efficacious, as …

AdultMaleMicrobiology (medical)medicine.medical_specialtyAntifungal AgentsNeutropeniaDrug-Related Side Effects and Adverse ReactionsCandidaemia; Caspofungin; Leukaemiamedicine.medical_treatmentAntineoplastic AgentsNeutropeniaEchinocandinsLipopeptidesYoung Adultchemistry.chemical_compoundPharmacotherapyCandidaemiaCaspofunginInternal medicinemedicineHumansLeukaemiaProspective StudiescaspofunginProspective cohort studyMycosisFungemiaAgedChemotherapyHematologybusiness.industryCandidiasisGeneral MedicineMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeInfectious DiseaseschemistryHematologic NeoplasmsleukaemiaFemaleCaspofunginbusinessFungemia
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A case of Candida krusei peritonitis secondary to duodenal perforation due to Candida duodenitis.

2011

A case of a 62-year-old man with Candida krusei peritonitis secondary to duodenal perforation due to Candida duodenitis that was successfully treated with a 14-day course of caspofungin is reported. The potential role of Candida infection in the pathogenesis of peptic ulcers and duodenal perforation is considered. If this role is confirmed, antifungal treatment should be included in the therapeutic armamentarium of peptic disease.

MalePeptic Ulcermedicine.medical_specialtyAntifungal AgentsVeterinary (miscellaneous)PepticPeritonitisPeritonitisApplied Microbiology and BiotechnologyMicrobiologyGastroenterologyPathogenesisEchinocandinsLipopeptideschemistry.chemical_compoundMedical microbiologyDuodenitisCaspofunginInternal medicineCandida kruseimedicineHumansDuodenal DiseasesDuodenal PerforationPeptic diseaseCandidaDuodenal perforationDuodenitibiologyPeritonitibusiness.industrySmokingCandidiasisCandida Peritonitis Duodenal perforation Duodenitis Peptic disease Caspofungin SmokingMiddle Agedmedicine.diseasebiology.organism_classificationdigestive system diseasesTreatment OutcomechemistryIntestinal PerforationCaspofunginbusinessAgronomy and Crop Science
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Evaluation of the Disk Diffusion Method Compared to the Microdilution Method in Susceptibility Testing of Anidulafungin against Filamentous Fungi

2008

ABSTRACT Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-μg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

Microbiology (medical)Susceptibility testingAntifungal AgentsDisk Diffusion; Yeasts; CaspofunginDisk diffusion anidulafungin MIC MECMycologyMicrobial Sensitivity TestsBiologyAnidulafunginSettore MED/42 - Igiene Generale E ApplicataDisk DiffusionMicrobiologyEchinocandinsCaspofunginYeastsmedicineHumansAgar diffusion testFood scienceAspergillus Anidulafungin Disk Diffusion1 3 β glucan synthaseAnidulafungineBroth microdilutionFungiAnidulafunginaMycosesAnidulafunginmedicine.drugJournal of Clinical Microbiology
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